Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 12/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846745 | 0.87 | CCNB2 (0.44) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL9846776 | 0.82 | CCNB2 (0.42) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL9846760 | 0.80 | L3MBTL1 (0.42) | SLC6A3NR1H2KMT2AHDAC1HDAC6 | |
| SCHEMBL9846753 | 0.80 | PTGDR2 (0.38) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL9846792 | 0.78 | AGTR1 (0.44) | — | |
| SCHEMBL9846741 | 0.77 | AGTR2 (0.52) | — | |
| SCHEMBL9846790 | 0.76 | AGTR1 (0.44) | — | |
| SCHEMBL9218501 | 0.76 | CCNB2 (0.37) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL10442198 | 0.76 | CHRM2 (0.49) | NR1H2NR1H3GABRG2GABRB3GABRA5 | |
| SCHEMBL9661962 | 0.75 | CCNB2 (0.39) | CCNB2CDK1CCNB1GSK3BCCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |