Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846760 | 0.85 | L3MBTL1 (0.42) | MAPTKMT2AMEN1L3MBTL1BRD4 | |
| SCHEMBL9846745 | 0.78 | CCNB2 (0.44) | MAPTKMT2AL3MBTL1LMNATP53 | |
| SCHEMBL30285064 | 0.77 | KMT2A (0.46) | MAPTKMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL1746797 | 0.76 | KMT2A (0.76) | MAPTKMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL29651126 | 0.76 | KMT2A (0.76) | MAPTKMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL9846763 | 0.76 | NR1H2 (0.51) | MAPTBRD4CREBBPLMNATP53 | |
| SCHEMBL16172322 | 0.74 | HTR6 (0.46) | MAPTKMT2AMEN1L3MBTL1BRD4 | |
| SCHEMBL2111547 | 0.74 | L3MBTL1 (0.48) | MAPTKMT2AMEN1L3MBTL1BRD4 | |
| SCHEMBL15902182 | 0.73 | HTR6 (0.46) | KMT2AMEN1L3MBTL1KDM4EBRD4 | |
| SCHEMBL29443980 | 0.73 | HTR6 (0.46) | KMT2AMEN1L3MBTL1KDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |