Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 8/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846721 | 0.76 | AGTR1 (0.64) | BRS3AGTR1AGTR2 | |
| SCHEMBL9846690 | 0.74 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9846718 | 0.74 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL9846736 | 0.74 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9846754 | 0.71 | BRS3 (0.38) | BRS3 | |
| SCHEMBL9846764 | 0.65 | AGTR1 (0.62) | BRS3AGTR1AGTR2 | |
| SCHEMBL9846750 | 0.62 | AGTR1 (0.48) | BRS3AGTR1AGTR2 | |
| SCHEMBL27657067 | 0.62 | KAT8 (0.62) | BRS3 | |
| SCHEMBL3906504 | 0.62 | BRS3 (0.70) | BRS3AGTR1AGTR2 | |
| SCHEMBL31522707 | 0.61 | GABRP (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |