Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 13/20 | 0.38 |
| ▸ | MDH2 | P40926 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846757 | 0.71 | BRS3 (0.43) | BRS3 | |
| SCHEMBL9846721 | 0.68 | AGTR1 (0.64) | BRS3 | |
| SCHEMBL9846736 | 0.67 | AGTR1 (0.57) | — | |
| SCHEMBL9846690 | 0.66 | AGTR1 (0.65) | PPARG | |
| SCHEMBL24966199 | 0.62 | ALDH1A1 (0.52) | — | |
| SCHEMBL28362059 | 0.62 | ALDH1A1 (0.52) | — | |
| SCHEMBL23931008 | 0.59 | HCAR3 (0.44) | CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL21653954 | 0.56 | BRS3 (0.70) | BRS3 | |
| SCHEMBL2504941 | 0.55 | KMT2A (0.45) | BRS3 | |
| SCHEMBL24966201 | 0.55 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |