SCHEMBL9846830

SCHEMBL9846830

CCCCOOOOCCCC

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.47
ADRB1 P08588 1/20 0.47
ADRB3 P13945 1/20 0.47
TSHR P16473 6/20 0.41
CYP3A4 P08684 2/20 0.41
LMNA P02545 1/20 0.40
ALDH1A1 P00352 2/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
THRB P10828 1/20 0.38
ATM Q13315 1/20 0.36
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LTA4H P09960 2/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL875488 0.93 ADRB2 (0.47) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL15658434 0.91 THRB (0.47) ADRB2ADRB1ADRB3TSHRCA1
SCHEMBL15660410 0.91 THRB (0.47) ADRB2ADRB1ADRB3TSHRCA1
SCHEMBL15656251 0.91 THRB (0.47) ADRB2ADRB1ADRB3TSHRCA1
SCHEMBL15658576 0.91 THRB (0.47) ADRB2ADRB1ADRB3TSHRCA1
SCHEMBL15732584 0.91 THRB (0.47) ADRB2ADRB1ADRB3TSHRCA1
Fluoride SCHEMBL28150033 0.90 ADRB2 (0.45) ADRB2ADRB1ADRB3TSHRCYP3A4
Phosphine SCHEMBL28347554 0.90 CYP3A4 (0.46) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL6938375 0.90 THRB (0.44) TSHRCA1CA2THRB
SCHEMBL29069326 0.87 THRB (0.41) TSHRCA1CA2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0422495-A1 Styrene polymer composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-04-17 EP disclosed
EP-0092624-B1 COATING COMPOSITION AND HYDROXY ACRYLIC COPOLYMER PRECURSOR THEREFOR E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-10-11 EP disclosed
US-4533695-A Non-aqueous dispersions based on capped stabilizers and reactants comprising polyfunctional monomers II FORD MOTOR COMPANY (US) 1985-08-06 US disclosed
US-4528317-A Non-aqueous dispersions based on capped stabilizers and reactants comprising polyfunctional monomers II FORD MOTOR COMPANY (US) 1985-07-09 US disclosed
EP-0092624-A2 Coating composition and hydroxy acrylic copolymer precursor therefor E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-11-02 EP disclosed
US-4394486-A High solids coatings with enhanced flexibility and impact strength FORD MOTOR COMPANY (US) 1983-07-19 US disclosed
US-4376187-A High solids urethane coatings with enhanced flexibility and impact strength FORD MOTOR COMPANY (US) 1983-03-08 US disclosed
US-4365068-A Crosslinkable bis-imidyl derivatives CIBA-GEIGY CORPORATION (US) 1982-12-21 US disclosed
US-4280946-A Crosslinkable bis-imidyl derivatives CIBA-GEIGY CORPORATION (US) 1981-07-28 US disclosed
US-4219481-A Crosslinkable bis-imidyl derivatives CIBA-GEIGY CORPORATION (US) 1980-08-26 US disclosed
US-4126619-A CROSSLINKABLE BIS-IMIDYL DERIVATIVES CIBA-GEIGY CORPORATION (US) 1978-11-21 US disclosed
US-4111771-A CROSSLINKABLE TETRA-IMIDYL DERIVATIVES AND CROSSLINKED POLYMERS THEREFROM CIBA-GEIGY CORPORATION (US) 1978-09-05 US disclosed
US-4085533-A IMMISCIBLE LIQUIDS EWALD ALFRED 1978-04-25 US disclosed