Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TOP2A | P11388 | 3/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846852 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL9846838 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL4788789 | 0.92 | TOP2A (0.41) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL4788784 | 0.92 | TOP2A (0.41) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL9139881 | 0.92 | TOP2A (0.41) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL9139167 | 0.82 | TOP2A (0.41) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL9139155 | 0.82 | TOP2A (0.41) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL14529652 | 0.78 | OPRM1 (0.41) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL8518182 | 0.75 | TOP2A (0.40) | ALDH1A1TOP2ATOP2BMAPTTDP1 | |
| SCHEMBL13103999 | 0.70 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409499-A2 | Pharmaceutical compositions | BTG INTERNATIONAL LIMITED (GB) | 1991-01-23 | — | — | EP | disclosed |