Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | BRS3 | P32247 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16489564 | 0.76 | KDM4C (0.56) | KDM4CKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL17052992 | 0.76 | ADRA2C (0.65) | KDM4CKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL25069004 | 0.74 | FFAR1 (0.48) | KDM4CKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL24435136 | 0.73 | KDM4C (0.54) | KDM4CKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL28799001 | 0.73 | KDM4C (0.60) | KDM4CKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL22191207 | 0.73 | KDM4E (0.56) | KDM4CKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL16489591 | 0.73 | KDM4C (0.60) | KDM4CKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL27847518 | 0.72 | KDM4C (0.67) | KDM4CKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL2511343 | 0.71 | KDM4C (0.57) | KDM4CKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL12859084 | 0.71 | HSD17B10 (0.53) | KDM4EADRA2CHPGDBACE1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435222-A2 | Aminopyridinylmethanols and aminomethylpyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-07-03 | — | — | EP | disclosed |