SCHEMBL24435136

SCHEMBL24435136

CC(C)Cc1ccncc1NCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 5/20 0.54
KDM4E B2RXH2 1/20 0.54
KDM6B O15054 1/20 0.54
KDM4A O75164 1/20 0.54
KDM4D Q6B0I6 1/20 0.54
KDM5B Q9UGL1 1/20 0.46
ADRA2C P18825 2/20 0.45
HPGD P15428 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
LTA4H P09960 1/20 0.43
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
MAPK10 P53779 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
BRS3 P32247 1/20 0.42
EGFR P00533 2/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24434902 0.74 HTR1A (0.42) ALDH1A1MEN1KMT2ALMNACYP3A4
SCHEMBL9846979 0.73 KDM4C (0.50) KDM4CKDM4EKDM6BKDM4AKDM4D
SCHEMBL17052992 0.73 ADRA2C (0.65) KDM4CKDM4EKDM6BKDM4AKDM4D
SCHEMBL22191378 0.73 KDM4C (0.60) KDM4CKDM4EKDM6BKDM4AKDM4D
SCHEMBL16489591 0.73 KDM4C (0.60) KDM4CKDM4EKDM6BKDM4AKDM4D
SCHEMBL2511343 0.71 KDM4C (0.57) KDM4CKDM4EKDM6BKDM4AKDM4D
SCHEMBL8567878 0.71 KDM4C (0.57) KDM4CKDM4EKDM6BKDM4AKDM4D
SCHEMBL24435135 0.71 ABCB1 (0.48) ALDH1A1LTA4HLMNA
SCHEMBL16489564 0.70 KDM4C (0.56) KDM4CKDM4EKDM6BKDM4AKDM4D
SCHEMBL22191207 0.70 KDM4E (0.56) KDM4CKDM4EKDM6BKDM4AKDM4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220153732-A1 PROTEIN SECRETION INHIBITORS ENODIA THERAPEUTICS SAS (FR) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153732-A1 PROTEIN SECRETION INHIBITORS SEC61B, SEC61A1, SEC61G KDM4C 4869/4885KDM4E 4710/4885KDM6B 4483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.