SCHEMBL9847102

SCHEMBL9847102

CCCc1ccc2nc(C)[nH]c2c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 3/20 0.35
ALDH1A1 P00352 1/20 0.35
KDM4E B2RXH2 2/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HSP90AA1 P07900 1/20 0.32
ESR2 Q92731 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ADORA3 P0DMS8 3/20 0.32
ADORA1 P30542 2/20 0.32
PARP1 P09874 2/20 0.32
ADORA2A P29274 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
HSD17B10 Q99714 2/20 0.31
PDK2 Q15119 1/20 0.31
GAA P10253 1/20 0.31
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847103 0.87 TYR (0.43) MAPTTDP1KMT2A
SCHEMBL18286706 0.86 TYMS (0.43) TYMSALDH1A1KDM4EMAPTHSP90AA1
SCHEMBL13383928 0.74 ALDH1A1 (0.48) TYMSALDH1A1KDM4EMAPTHSP90AA1
SCHEMBL353027 0.74 ALDH1A1 (0.41) TYMSALDH1A1KDM4EMAPTMAPK1
SCHEMBL9847101 0.72 ADRB2 (0.42) ALDH1A1KDM4EADORA3ADORA1PARP1
SCHEMBL28193852 0.72 PARP1 (0.37) ALDH1A1KDM4EPARP1POLBKMT2A
SCHEMBL6142611 0.71 ALDH1A1 (0.40) TYMSALDH1A1KDM4EMAPTHSP90AA1
SCHEMBL22011133 0.71 CSNK2A1 (0.39) TYMSALDH1A1KDM4EMAPTHSP90AA1
SCHEMBL25710808 0.71 ALDH1A1 (0.43) TYMSALDH1A1KDM4EMAPTHSP90AA1
SCHEMBL12020719 0.71 ALDH1A1 (0.47) TYMSALDH1A1KDM4EMAPTHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0428260-A2 Metal surface treatment agents SANWA LABORATORY LTD. (JP) 1991-05-22 EP claimed