SCHEMBL9847155

SCHEMBL9847155

COC(=O)C(C)Oc1cc(Oc2ncc(C(F)(F)F)cc2Cl)ccc1/C=N/Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 1/20 0.49
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
RAB9A P51151 1/20 0.46
PPARG P37231 4/20 0.46
ALDH1A1 P00352 2/20 0.45
KMT2A Q03164 2/20 0.44
MAPT P10636 2/20 0.44
XBP1 P17861 2/20 0.44
MEN1 O00255 1/20 0.44
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ATM Q13315 1/20 0.44
FFAR1 O14842 1/20 0.44
MAPK1 P28482 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C19 P33261 1/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9826529 1.00 LIPE (0.49) LIPELMNASMN1; SMN2RAB9APPARG
SCHEMBL9828236 0.86 LMNA (0.53) LIPELMNASMN1; SMN2RAB9APPARG
SCHEMBL9827148 0.81 MAPT (0.45) LMNASMN1; SMN2RAB9APPARGALDH1A1
SCHEMBL9827144 0.81 MAPT (0.45) LMNASMN1; SMN2RAB9APPARGALDH1A1
SCHEMBL9827997 0.81 FFAR1 (0.48) PPARGKMT2AMEN1FFAR1TDP1
SCHEMBL9827993 0.81 FFAR1 (0.48) PPARGKMT2AMEN1FFAR1TDP1
SCHEMBL10573318 0.80 LMNA (0.56) LIPELMNASMN1; SMN2RAB9APPARG
Haloxyfop-P-Methyl SCHEMBL29514646 0.80 LMNA (0.65) LIPELMNASMN1; SMN2RAB9AALDH1A1
Haloxyfop-P-Methyl SCHEMBL54547 0.80 LMNA (0.65) LIPELMNASMN1; SMN2RAB9AALDH1A1
Haloxyfop-P-Methyl SCHEMBL54814 0.80 LMNA (0.65) LIPELMNASMN1; SMN2RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0442172-A1 Oxime derivatives and Herbicides containing the same as an active ingredient TEIJIN LIMITED (JP) 1991-08-21 EP disclosed