Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10441957 | 0.80 | TNF (0.30) | — | |
| SCHEMBL25273577 | 0.74 | ALDH1A1 (0.30) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL23851052 | 0.69 | ADORA2A (0.30) | — | |
| SCHEMBL22867173 | 0.68 | WDR5 (0.34) | — | |
| SCHEMBL3821407 | 0.67 | KDM4E (0.35) | — | |
| SCHEMBL18029737 | 0.65 | CYP19A1 (0.42) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL28762859 | 0.64 | KMT2A (0.38) | ALDH1A1HSD17B10 | |
| SCHEMBL8779774 | 0.64 | ALDH1A1 (0.36) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL427634 | 0.61 | TDP1 (0.43) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL4354712 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375061-A1 | Preparation of 5-amino-1,2,4-triazole-3-sulfonamides and intermediates | DowElanco (US) | 1990-06-27 | — | — | EP | claimed |
| EP-0427336-A1 | Process for the preparation of 5-amino-3-chlorosulfonyl-1,2,4-triazole | DOWELANCO (US) | 1991-05-15 | — | — | EP | disclosed |
| EP-0375061-A1 | Preparation of 5-amino-1,2,4-triazole-3-sulfonamides and intermediates | DowElanco (US) | 1990-06-27 | — | — | EP | disclosed |