SCHEMBL9847548

SCHEMBL9847548

CCOC1CC(C)c2ccc(Oc3ccc(NC(=O)N(C)OC)cc3)cc2O1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
PKM P14618 1/20 0.40
RAB9A P51151 1/20 0.40
MTNR1B P49286 9/20 0.38
MTNR1A P48039 6/20 0.38
NPY5R Q15761 4/20 0.35
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847535 0.90 MEN1 (0.43) KMT2AMEN1TDP1PKMRAB9A
SCHEMBL9847554 0.85 MTNR1B (0.40) KMT2AMEN1RAB9AMTNR1BMTNR1A
SCHEMBL9847634 0.82 MEN1 (0.40) KMT2AMEN1TDP1PKMRAB9A
SCHEMBL9847580 0.77 MEN1 (0.39) KMT2AMEN1TDP1PKMRAB9A
SCHEMBL9847546 0.76 MTNR1B (0.40) RAB9AMTNR1BMTNR1A
SCHEMBL9847564 0.75 MEN1 (0.41) KMT2AMEN1TDP1PKMRAB9A
SCHEMBL9847538 0.74
SCHEMBL9847529 0.73 MEN1 (0.43) KMT2AMEN1TDP1PKMRAB9A
SCHEMBL11179851 0.72 MTNR1B (0.56) KMT2AMEN1TDP1PKMRAB9A
SCHEMBL11180089 0.69 MTNR1B (0.70) KMT2AMEN1TDP1PKMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434074-A2 Process for the production of 1-lower alkoxy-1-lower alkyl-3-substituted phenylurea, and intermediate thereof and process for the production of the intermediate MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-06-26 EP disclosed