SCHEMBL9847634

SCHEMBL9847634

CCOC1CCc2ccc(Oc3ccc(NC(=O)N(C)OC)cc3)cc2O1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
PKM P14618 1/20 0.40
RAB9A P51151 1/20 0.40
NPY5R Q15761 4/20 0.40
MCHR1 Q99705 1/20 0.40
PPARG P37231 2/20 0.38
PPARA Q07869 2/20 0.38
PPARD Q03181 1/20 0.38
EPHX2 P34913 1/20 0.37
MTNR1A P48039 3/20 0.37
MTNR1B P49286 3/20 0.37
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
ACHE P22303 2/20 0.36
ALDH1A1 P00352 1/20 0.35
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847529 0.90 MEN1 (0.43) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL9847618 0.85 EPHX2 (0.43) KMT2ATDP1PKMRAB9ANPY5R
SCHEMBL9847548 0.82 KMT2A (0.40) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL9847625 0.77 ALDH1A1 (0.43) MEN1KMT2ATDP1RAB9APPARG
SCHEMBL9847645 0.76 PPARA (0.40) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL9847595 0.76 MCHR1 (0.42) TDP1RAB9ANPY5RMCHR1PPARG
SCHEMBL6508806 0.75 DRD2 (0.45) MTNR1AMTNR1BCA2FFAR1
SCHEMBL9847581 0.75 PPARG (0.43) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL9847598 0.74 PPARG (0.37) PPARGPPARAPPARDMTNR1BFFAR1
SCHEMBL9847535 0.73 MEN1 (0.43) MEN1KMT2ATDP1PKMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434074-A2 Process for the production of 1-lower alkoxy-1-lower alkyl-3-substituted phenylurea, and intermediate thereof and process for the production of the intermediate MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-06-26 EP disclosed