Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 8/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.40 |
| ▸ | RAF1 | P04049 | 3/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847554 | 0.89 | MTNR1B (0.40) | MTNR1BMTNR1AEPHX2NPC1RAB9A | |
| SCHEMBL9847535 | 0.85 | MEN1 (0.43) | MTNR1BMTNR1APGRRAB9A | |
| SCHEMBL9847595 | 0.80 | MCHR1 (0.42) | MTNR1BMTNR1AEPHX2NPC1RAB9A | |
| SCHEMBL9847608 | 0.77 | MTNR1B (0.39) | MTNR1BMTNR1ARAF1CDK8PGR | |
| SCHEMBL9847548 | 0.76 | KMT2A (0.40) | MTNR1BMTNR1ARAB9A | |
| SCHEMBL9847627 | 0.75 | MTNR1B (0.41) | MTNR1BMTNR1ARAF1EPHX2SMN1; SMN2 | |
| SCHEMBL9847618 | 0.71 | EPHX2 (0.43) | MTNR1BMTNR1AEPHX2NPC1RAB9A | |
| SCHEMBL9847646 | 0.69 | HIF1A (0.37) | MTNR1BMTNR1ARAF1EPHX2NPC1 | |
| SCHEMBL9847552 | 0.66 | ALDH1A1 (0.42) | NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL9754850 | 0.66 | MTNR1B (0.38) | MTNR1BMTNR1ARAF1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434074-A2 | Process for the production of 1-lower alkoxy-1-lower alkyl-3-substituted phenylurea, and intermediate thereof and process for the production of the intermediate | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |