SCHEMBL9847565

SCHEMBL9847565

CCC1(OC)CCc2ccc(Oc3ccc(NC(=O)NO)cc3)cc2O1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARG P37231 15/20 0.44
PPARA Q07869 15/20 0.44
MTNR1B P49286 1/20 0.40
POLB P06746 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
MCHR1 Q99705 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847581 0.86 PPARG (0.43) PPARGPPARATDP1RAB9A
SCHEMBL9847575 0.85 PPARG (0.40) PPARGPPARAMTNR1BPOLBNPC1
SCHEMBL9847547 0.82 PPARA (0.42) PPARGPPARAMTNR1BPOLBTDP1
SCHEMBL9847627 0.80 MTNR1B (0.41) MTNR1B
SCHEMBL9847551 0.80 PPARG (0.43) PPARGPPARA
SCHEMBL9847586 0.78 PPARA (0.38) PPARGPPARAMTNR1BPOLBNPC1
SCHEMBL9847571 0.76 PPARG (0.42) PPARGPPARA
SCHEMBL9847646 0.75 HIF1A (0.37) MTNR1BPOLBNPC1RAB9AMCHR1
SCHEMBL9847595 0.73 MCHR1 (0.42) PPARGPPARAMTNR1BPOLBTDP1
SCHEMBL9847618 0.73 EPHX2 (0.43) PPARGPPARAMTNR1BPOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434074-A2 Process for the production of 1-lower alkoxy-1-lower alkyl-3-substituted phenylurea, and intermediate thereof and process for the production of the intermediate MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-06-26 EP disclosed