SCHEMBL9847595

SCHEMBL9847595

COC1CCc2ccc(Oc3ccc(NC(=O)NO)cc3)cc2O1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.42
MTNR1B P49286 4/20 0.41
MTNR1A P48039 3/20 0.41
POLB P06746 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
EPHX2 P34913 2/20 0.39
NPY5R Q15761 1/20 0.38
PPARG P37231 2/20 0.37
PPARA Q07869 2/20 0.37
EPHX1 P07099 2/20 0.37
PPARD Q03181 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847618 0.89 EPHX2 (0.43) MCHR1MTNR1BMTNR1APOLBNPC1
SCHEMBL9847529 0.85 MEN1 (0.43) MCHR1MTNR1BMTNR1ARAB9ANPY5R
SCHEMBL9847546 0.80 MTNR1B (0.40) MTNR1BMTNR1ANPC1RAB9AEPHX2
SCHEMBL9847659 0.78 ALDH1A1 (0.46) POLBNPC1RAB9APPARGPPARA
SCHEMBL9847634 0.76 MEN1 (0.40) MCHR1MTNR1BMTNR1ARAB9AEPHX2
SCHEMBL9847575 0.75 PPARG (0.40) MTNR1BMTNR1APOLBNPC1RAB9A
SCHEMBL9847567 0.74 PPARG (0.35) MTNR1BPPARGPPARAPPARD
SCHEMBL6505490 0.74 CA2 (0.48) MTNR1B
SCHEMBL9847565 0.73 PPARG (0.44) MCHR1MTNR1BPOLBNPC1RAB9A
SCHEMBL27610322 0.72 ESR1 (0.34) NFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434074-A2 Process for the production of 1-lower alkoxy-1-lower alkyl-3-substituted phenylurea, and intermediate thereof and process for the production of the intermediate MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-06-26 EP disclosed