SCHEMBL9847586

SCHEMBL9847586

CC(C)OC1(C)CCc2ccc(Oc3ccc(NC(=O)NO)cc3)cc2O1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 12/20 0.38
PPARG P37231 11/20 0.38
PPARD Q03181 4/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ANPEP P15144 1/20 0.36
POLB P06746 2/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
MTNR1B P49286 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847575 0.89 PPARG (0.40) PPARAPPARGPPARDMEN1KMT2A
SCHEMBL9847547 0.86 PPARA (0.42) PPARAPPARGPPARDPOLBMTNR1B
SCHEMBL9847611 0.85 MEN1 (0.40) PPARAPPARGPPARDMEN1KMT2A
SCHEMBL9847572 0.84 MEN1 (0.38) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL9847593 0.80 ALDH1A1 (0.42) PPARAPPARGPPARDMEN1KMT2A
SCHEMBL9847565 0.78 PPARG (0.44) PPARAPPARGPOLBNPC1RAB9A
SCHEMBL9847532 0.76 PPARA (0.36) PPARAPPARGPPARD
SCHEMBL9847644 0.75 MEN1 (0.43) PPARAPPARGPPARDMEN1KMT2A
SCHEMBL9754850 0.74 MTNR1B (0.38) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL9847646 0.73 HIF1A (0.37) MEN1KMT2APOLBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434074-A2 Process for the production of 1-lower alkoxy-1-lower alkyl-3-substituted phenylurea, and intermediate thereof and process for the production of the intermediate MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-06-26 EP disclosed