Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16657361 | 0.84 | EGFR (0.51) | MAPK14HDAC1HDAC2EGFRMAPT | |
| SCHEMBL29581611 | 0.83 | MAPK14 (0.56) | MAPK14HDAC1HDAC2EGFRHDAC3 | |
| SCHEMBL28141830 | 0.82 | ABCB1 (0.55) | MAPK14EGFRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28288683 | 0.82 | NPC1 (0.51) | MAPK14EGFRMAPTALDH1A1HTT | |
| SCHEMBL18796082 | 0.81 | NPSR1 (0.53) | MAPK14HDAC1HDAC2MAPTKDM4E | |
| SCHEMBL379439 | 0.80 | GRM4 (0.57) | MAPK14EGFRMAPTKDM4ETP53 | |
| SCHEMBL1008997 | 0.79 | NPC1 (0.58) | EGFRMAPTKDM4ETP53SMN1; SMN2 | |
| SCHEMBL1011248 | 0.79 | PABPC1 (0.59) | EGFRMAPTKDM4ETP53SMN1; SMN2 | |
| SCHEMBL4944938 | 0.79 | MAPK14 (0.67) | MAPK14MAPTKDM4ETP53SMN1; SMN2 | |
| SCHEMBL29581107 | 0.78 | MAPK14 (0.49) | MAPK14HDAC1HDAC2HDAC3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432091-A1 | Heat sensitive recording material | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |