Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560040 | 0.91 | AGTR1 (0.52) | AGTR1AGTR2KDM4E | |
| Ammonia Solution, Strong SCHEMBL8563437 | 0.90 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9847777 | 0.87 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9847846 | 0.85 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9847782 | 0.85 | AGTR2 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9847884 | 0.85 | AGTR2 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9847838 | 0.84 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL7050680 | 0.84 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9847869 | 0.84 | AGTR2 (0.47) | AGTR1AGTR2 | |
| Ammonia Solution, Strong SCHEMBL9847783 | 0.84 | AGTR1 (0.43) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | claimed |
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | disclosed |