Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 7/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8971516 | 0.90 | AGTR1 (0.51) | AGTR1AGTR2HTR6HTR1ADRD2 | |
| SCHEMBL9847884 | 0.86 | AGTR2 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9847777 | 0.86 | AGTR1 (0.52) | AGTR1AGTR2HTR6 | |
| SCHEMBL9847836 | 0.85 | AGTR2 (0.42) | AGTR1AGTR2HTR1A | |
| SCHEMBL9847838 | 0.85 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9847788 | 0.85 | MEN1 (0.37) | AGTR1AGTR2HTR6HTR1ADRD2 | |
| SCHEMBL9847782 | 0.84 | AGTR2 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9847846 | 0.84 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9847792 | 0.84 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9847837 | 0.84 | AGTR1 (0.58) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | disclosed |