Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12066584 | 0.84 | TDP1 (0.52) | TSHRTDP1ATMALDH1A1CYP3A4 | |
| SCHEMBL31226260 | 0.83 | ALDH1A1 (0.50) | TSHRTDP1MAPK1ATMALDH1A1 | |
| SCHEMBL9693389 | 0.83 | ALDH1A1 (0.54) | TSHRTDP1MAPK1ATMALDH1A1 | |
| SCHEMBL9693778 | 0.82 | GPR35 (0.61) | TSHRTDP1MAPK1ALDH1A1CYP3A4 | |
| SCHEMBL8526617 | 0.81 | TSHR (0.45) | TSHRTDP1MAPK1ATMALDH1A1 | |
| SCHEMBL31236206 | 0.81 | TSHR (0.45) | TSHRTDP1MAPK1ATMALDH1A1 | |
| SCHEMBL1822002 | 0.80 | TDP1 (0.61) | TSHRTDP1MAPK1ATMALDH1A1 | |
| SCHEMBL17429460 | 0.80 | CYP1A2 (0.43) | TSHRTDP1MAPK1ATMALDH1A1 | |
| SCHEMBL103341 | 0.80 | GPR35 (0.65) | TDP1MAPK1ALDH1A1CYP3A4HIF1A | |
| SCHEMBL4707083 | 0.80 | ALDH1A1 (0.52) | TSHRTDP1MAPK1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250430-A1 | BICYCLIC AMINE CDK12 INHIBITORS | INCYTE CORPORATION (US) | 2023-12-28 | — | — | WO | disclosed |
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | disclosed |