Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693289 | 0.89 | TSHR (0.48) | ALDH1A1TSHRMAPK1HIF1AVCAM1 | |
| SCHEMBL1467467 | 0.83 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPK1HIF1AVCAM1 | |
| SCHEMBL9847876 | 0.83 | TSHR (0.44) | ALDH1A1TSHRMAPK1HIF1AVCAM1 | |
| SCHEMBL9693778 | 0.82 | GPR35 (0.61) | ALDH1A1TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL31236206 | 0.81 | TSHR (0.45) | ALDH1A1TSHRMAPK1HIF1AVCAM1 | |
| SCHEMBL8526617 | 0.81 | TSHR (0.45) | ALDH1A1TSHRMAPK1HIF1AVCAM1 | |
| SCHEMBL18669411 | 0.80 | GPR35 (0.46) | ALDH1A1TSHRMAPK1HIF1AVCAM1 | |
| SCHEMBL25950214 | 0.80 | TSHR (0.41) | ALDH1A1TSHRMAPK1HIF1AVCAM1 | |
| SCHEMBL18669404 | 0.80 | ERN1 (0.42) | ALDH1A1TSHRMAPK1HIF1AVCAM1 | |
| SCHEMBL20471887 | 0.80 | PDE7A (0.43) | ALDH1A1TSHRMAPK1HIF1AVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130744-B | A kind of 2,4 difluoro 3,5 dichloronitrobenzene synthesis 1,3,5 trichlorine, 2,4,6 trifluoro-benzene | 浙江林江化工股份有限公司 | 2017-03-29 | — | — | CN | claimed |
| CN-1683318-A | Synthetic method for 3,5-dichloro-2,4-difluoronitrobenzene and teflubenzuron | UNIV ZHEJIANG POLYTECHNIC (CN) | 2005-10-19 | — | — | CN | claimed |
| CN-1020599-C | PROCESS FOR PREPARATION OF ACYL UREAS | SHELL INT RESEARCH (NL) | 1993-05-12 | — | — | CN | claimed |
| CN-86108203-A | Process for preparing acyl ureas | — | 1987-09-02 | — | — | CN | claimed |
| CN-110191882-B | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | 株式会社大熊制药 | 2022-09-13 | — | — | CN | disclosed |
| US-10981917-B2 | Heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2021-04-20 | — | — | US | disclosed |
| WO-2018147626-A1 | NOVEL HETEROCYCLIC COMPOUND, ITS PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2018-08-16 | — | — | WO | disclosed |
| CN-105130744-B | A kind of 2,4 difluoro 3,5 dichloronitrobenzene synthesis 1,3,5 trichlorine, 2,4,6 trifluoro-benzene | 浙江林江化工股份有限公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-105130744-A | Method for synthesizing 1,3,5-trichloro-2,4,6-trifluorobenzene from 2,4-difluoro-3,5-dichloronitrobenzene | ZHEJIANG LINJIANG CHEMICAL CO LTD | 2015-12-09 | — | — | CN | disclosed |
| CN-102617360-B | Synthetic method of 3, 5-dichloro-2, 4-difluoroaniline | JIANGXI JIXIANG PHARMACEUTICAL CO LTD | 2013-11-06 | — | — | CN | disclosed |
| CN-102617360-A | Synthetic method of 3, 5-dichloro-2, 4-difluoroaniline | JIANGXI JIXIANG PHARMACEUTICAL CO LTD | 2012-08-01 | — | — | CN | disclosed |
| CN-1020599-C | PROCESS FOR PREPARATION OF ACYL UREAS | SHELL INT RESEARCH (NL) | 1993-05-12 | — | — | CN | disclosed |
| EP-0270964-B1 | PROCESS FOR OBTAINING SUBSTITUTED FLUOROBENZENES | BAYER AG (DE) | 1992-07-08 | — | — | EP | disclosed |
| EP-0270964-A2 | Process for obtaining substituted fluorobenzenes | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |
| CN-86108203-A | Process for preparing acyl ureas | — | 1987-09-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981917-B2 | Heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same | RNASE1, AARS1, DHPS | ALDH1A1 2364/4885TSHR 1348/4885MAPK1 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.