Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12479933 | 0.81 | KMT2A (0.51) | KMT2AMEN1CREBBPALDH1A1KDM4E | |
| SCHEMBL9848046 | 0.81 | OXER1 (0.43) | KDM4ELMNAL3MBTL1 | |
| SCHEMBL8359818 | 0.81 | KMT2A (0.60) | KMT2AMEN1CREBBPALDH1A1KDM4E | |
| SCHEMBL21725009 | 0.77 | KMT2A (0.49) | KMT2AMEN1CREBBPALDH1A1KDM4E | |
| SCHEMBL12479862 | 0.76 | ALDH1A1 (0.48) | KMT2AMEN1CREBBPALDH1A1KDM4E | |
| SCHEMBL8528867 | 0.74 | KMT2A (0.43) | KMT2AMEN1CREBBPALDH1A1KDM4E | |
| SCHEMBL8528870 | 0.74 | TFPI2 (0.47) | KMT2AMEN1ALDH1A1KDM4ETHRB | |
| SCHEMBL15597217 | 0.73 | KDM4E (0.47) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL30394690 | 0.71 | CREBBP (0.58) | KMT2AMEN1CREBBPALDH1A1KDM4E | |
| SCHEMBL12479991 | 0.71 | KMT2A (0.51) | KMT2AMEN1ALDH1A1KDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |