Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720058 | 0.83 | CTSK (0.37) | ALDH1A1GLAHPGDSMN1; SMN2POLB | |
| SCHEMBL9848039 | 0.80 | MTNR1A (0.47) | ALDH1A1GLAHPGDCACNA2D1 | |
| SCHEMBL9848055 | 0.76 | MGLL (0.32) | — | |
| SCHEMBL9848037 | 0.75 | POLB (0.57) | ALDH1A1GLAHPGDPOLBLTA4H | |
| SCHEMBL9848048 | 0.72 | MAPK1 (0.42) | ALDH1A1SMN1; SMN2ACEPOLBSIGMAR1 | |
| SCHEMBL9582659 | 0.69 | CTSC (0.45) | ALDH1A1GLAHPGDPOLB | |
| SCHEMBL9582418 | 0.68 | CTSC (0.43) | ALDH1A1GLAHPGDACESLC18A2 | |
| SCHEMBL20408407 | 0.68 | ACE (0.46) | ACESIGMAR1 | |
| SCHEMBL9906029 | 0.68 | ACE (0.46) | ACESIGMAR1 | |
| SCHEMBL9851119 | 0.67 | MGLL (0.39) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406661-A1 | Substituted 3-aminosydnonimines, process for their preparation, and their use | CASSELLA Aktiengesellschaft (DE) | 1991-01-09 | — | — | EP | disclosed |