Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | APP | P05067 | 10/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2969912 | 0.82 | RAB9A (0.54) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6696955 | 0.81 | RAB9A (0.42) | MAPTKDM4EALDH1A1APPSMN1; SMN2 | |
| SCHEMBL11287805 | 0.79 | MEN1 (0.52) | MAPTKDM4EALDH1A1APPSMN1; SMN2 | |
| SCHEMBL6618761 | 0.77 | KDM4E (0.38) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL13680449 | 0.76 | CCR1 (0.56) | MAPTKDM4EALDH1A1APPSMN1; SMN2 | |
| SCHEMBL6621303 | 0.76 | KDM4E (0.50) | MAPTKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL6701320 | 0.76 | KDM4E (0.37) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL6618175 | 0.75 | NOS1 (0.36) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL6700787 | 0.75 | CYP2A6 (0.53) | ALDH1A1APPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6618202 | 0.75 | IRAK4 (0.40) | MAPTKDM4EALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451585-A2 | 2-aryl-6-hetarylpyridine derivatives | BAYER AG (DE) | 1991-10-16 | — | — | EP | claimed |
| EP-0451585-A2 | 2-aryl-6-hetarylpyridine derivatives | BAYER AG (DE) | 1991-10-16 | — | — | EP | disclosed |