Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA7 | P43166 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LSS | P48449 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312666 | 0.82 | MAPT (0.53) | ALDH1A1LMNACA1CA2CA7 | |
| SCHEMBL9311736 | 0.78 | MAPK10 (0.61) | ALDH1A1LMNACA1CA2CA7 | |
| SCHEMBL28180887 | 0.77 | ALDH1A1 (0.76) | ALDH1A1LMNACA1CA2CA7 | |
| SCHEMBL31011321 | 0.77 | ALDH1A1 (0.76) | ALDH1A1LMNACA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL9312979 | 0.77 | MAPK10 (0.60) | ALDH1A1LMNACA1CA2CA7 | |
| SCHEMBL9312347 | 0.77 | MAPK10 (0.63) | ALDH1A1LMNACA1CA2CA7 | |
| SCHEMBL5353435 | 0.75 | MAPK10 (0.60) | ALDH1A1LMNACA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL9311868 | 0.74 | MAPK10 (0.59) | ALDH1A1LMNACA1CA2CA7 | |
| SCHEMBL17144585 | 0.70 | CA1 (0.66) | ALDH1A1LMNACA1CA2CA7 | |
| SCHEMBL983184 | 0.69 | CA1 (0.66) | ALDH1A1LMNACA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422328-A2 | Substituted isoquinolines and their use | Euro-Celtique S.A. (LU) | 1991-04-17 | — | — | EP | disclosed |
| US-4956371-A | PLATELET ACTIVATING FACTOR | EUROCELTIQUE, S.A. (LU) | 1990-09-11 | — | — | US | disclosed |