Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6722898 | 0.87 | CA1 (0.60) | MAPTMAPK1ALDH1A1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL6716745 | 0.86 | CA1 (0.58) | MAPTMAPK1ALDH1A1LMNAKDM4E | |
| SCHEMBL10967087 | 0.85 | KDM4E (0.74) | MAPTMAPK1ALDH1A1LMNAKDM4E | |
| SCHEMBL9848138 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNAKDM4EMAPK10CA1 | |
| SCHEMBL5353435 | 0.79 | MAPK10 (0.60) | MAPTALDH1A1LMNAMAPK10CA1 | |
| SCHEMBL7989235 | 0.79 | ACHE (0.48) | MAPTMAPK1ALDH1A1LMNAKDM4E | |
| SCHEMBL11715443 | 0.79 | MAPK10 (0.65) | ALDH1A1LMNAKDM4EMAPK10GLA | |
| SCHEMBL11719015 | 0.79 | MAPK10 (0.65) | ALDH1A1LMNAKDM4EMAPK10GLA | |
| SCHEMBL9312347 | 0.78 | MAPK10 (0.63) | MAPTALDH1A1LMNAMAPK10CA1 | |
| Hydrochloric Acid SCHEMBL11713492 | 0.78 | MAPK10 (0.63) | MAPTALDH1A1LMNAKDM4EMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34630-E | Antagonist for platelet activating factor | EUROCELTIQUE, S.A. (LU) | 1994-06-07 | — | — | US | disclosed |
| EP-0422328-A2 | Substituted isoquinolines and their use | Euro-Celtique S.A. (LU) | 1991-04-17 | — | — | EP | disclosed |
| US-4956371-A | PLATELET ACTIVATING FACTOR | EUROCELTIQUE, S.A. (LU) | 1990-09-11 | — | — | US | disclosed |