SCHEMBL9848273

SCHEMBL9848273

O=C(O)CCCNc1ccc(S)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
POLB P06746 2/20 0.47
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42
MAPT P10636 2/20 0.42
FFAR1 O14842 2/20 0.42
CDC25A P30304 1/20 0.42
CDC25B P30305 1/20 0.42
LMNA P02545 2/20 0.41
EPHX2 P34913 1/20 0.41
ATM Q13315 1/20 0.41
MEN1 O00255 1/20 0.41
TSHR P16473 1/20 0.41
CASP1 P29466 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9167772 0.89 POLB (0.59) ALDH1A1POLBGRIN2DGRIN3BGRIN1
SCHEMBL15613904 0.83 LMNA (0.58) ALDH1A1POLBGRIN2DGRIN3BGRIN1
SCHEMBL2177141 0.82 ALDH1A1 (0.64) ALDH1A1POLBMAPTFFAR1CDC25A
SCHEMBL9848269 0.81 ALDH1A1 (0.51) ALDH1A1POLBGRIN2DGRIN3BGRIN1
SCHEMBL4828296 0.81 ALDH1A1 (0.51) ALDH1A1POLBGRIN2DGRIN3BGRIN1
SCHEMBL23794429 0.81 MAPT (0.57) ALDH1A1POLBMAPTFFAR1LMNA
SCHEMBL27609848 0.81 ALDH1A1 (0.61) ALDH1A1POLBMAPTFFAR1CDC25A
SCHEMBL27591545 0.81 ALDH1A1 (0.61) ALDH1A1POLBMAPTFFAR1CDC25A
SCHEMBL27797433 0.80 MAPT (0.55) ALDH1A1POLBMAPTFFAR1CDC25A
SCHEMBL15613891 0.79 HSD17B10 (0.57) ALDH1A1POLBMAPTEPHX2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0451526-A2 Silver halide colour photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1991-10-16 EP disclosed