Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925202 | 0.85 | P2RX7 (0.49) | HPGDALDH1A1MAPK14GAAP2RX7 | |
| SCHEMBL2799566 | 0.84 | THRB (0.55) | HPGDALDH1A1MAPK14SMN1; SMN2HDAC1 | |
| SCHEMBL18132548 | 0.83 | HTT (0.62) | HPGDALDH1A1GAALMNAMAPT | |
| SCHEMBL23805008 | 0.80 | P2RX7 (0.48) | ALDH1A1SMN1; SMN2MAPTP2RX7NPC1 | |
| SCHEMBL26728285 | 0.80 | P2RX7 (0.51) | ALDH1A1GAAP2RX7RAB9A | |
| SCHEMBL31036963 | 0.77 | P2RX7 (0.55) | ALDH1A1GAAHTTP2RX7NPC1 | |
| SCHEMBL10630135 | 0.77 | GAA (0.53) | HPGDALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL10065403 | 0.77 | P2RX7 (0.49) | ALDH1A1GAAP2RX7NPC1RAB9A | |
| SCHEMBL10604929 | 0.76 | HPGD (0.67) | HPGDALDH1A1SMN1; SMN2GAATTR | |
| SCHEMBL5723909 | 0.76 | HPGD (0.67) | HPGDALDH1A1SMN1; SMN2GAATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |