Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848576 | 1.00 | CSNK1A1 (0.41) | CSNK1A1CLK4CYP2D6MAOAMAPK1 | |
| SCHEMBL7280206 | 0.78 | KMT2A (0.34) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL7280211 | 0.78 | KMT2A (0.34) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL9848552 | 0.75 | CSNK1A1 (0.53) | CSNK1A1CLK4CYP2D6MAOAMAPK1 | |
| SCHEMBL7272766 | 0.75 | ALDH1A1 (0.37) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL7272773 | 0.75 | ALDH1A1 (0.37) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL11133814 | 0.73 | KMT2A (0.47) | MAPK1ADRA1AKMT2AKDM4EALDH1A1 | |
| SCHEMBL11133816 | 0.73 | KMT2A (0.47) | MAPK1ADRA1AKMT2AKDM4EALDH1A1 | |
| SCHEMBL3929311 | 0.70 | ADORA2A (0.62) | CSNK1A1CLK4CYP2D6MAOAMAPK1 | |
| SCHEMBL9081729 | 0.69 | CCNA2 (0.40) | MAPK1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459829-A1 | Pharmacologically active CNS compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |