Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.45 |
| ▸ | TXNRD3 | Q86VQ6 | 2/20 | 0.45 |
| ▸ | TXNRD2 | Q9NNW7 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957884 | 1.00 | ALDH1A1 (0.61) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL13767769 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL11264900 | 0.84 | TSHR (0.53) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL11264895 | 0.84 | TSHR (0.53) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL3858732 | 0.83 | HSD17B10 (0.51) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL1096483 | 0.83 | PTGS2 (0.47) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL405375 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL440162 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL3357419 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL7407755 | 0.83 | PTGS2 (0.47) | ALDH1A1MAPTTDP1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409025-A2 | N-[Indol-6-yl]-heterocyclic compounds | BAYER AG (DE) | 1991-01-23 | — | — | EP | disclosed |
| US-3976639-A | Intermediates for indoles | HOFFMANN-LA ROCHE INC. (US) | 1976-08-24 | — | — | US | disclosed |