Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.54 |
| ▸ | MME | P08473 | 4/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 2/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPA3 | P15088 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185519 | 0.80 | CTSC (0.54) | — | |
| SCHEMBL7170005 | 0.80 | CTSC (0.54) | LTA4HMME | |
| SCHEMBL2197602 | 0.80 | BACE1 (0.53) | LTA4H | |
| SCHEMBL2183798 | 0.79 | CTSC (0.62) | MME | |
| SCHEMBL25176537 | 0.78 | CASP3 (0.57) | CASP3CASP1CASP7 | |
| SCHEMBL11596134 | 0.77 | CTSC (0.66) | LTA4HMMECPA1CPB1CPA3 | |
| SCHEMBL7296578 | 0.75 | CASP1 (0.54) | LTA4HCASP1 | |
| SCHEMBL12434601 | 0.75 | CASP1 (0.54) | LTA4HCASP1 | |
| SCHEMBL7292855 | 0.74 | MMP2 (0.51) | — | |
| SCHEMBL7292856 | 0.74 | MMP2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438873-A1 | Inhibitor of ribonucleotide reductase of herpes viruses | MERCK & CO. INC. (US) | 1991-07-31 | — | — | EP | disclosed |