SCHEMBL9848705

CC(C)C[C@@H]([C]=O)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	14/20	0.43

▸	CTSD	P07339	2/20	0.39

▸	REN	P00797	3/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9848617	0.90	BACE1 (0.38)	BACE1CTSDREN
SCHEMBL9848678	0.83	BACE1 (0.42)	BACE1CTSDREN
SCHEMBL30153240	0.78	BACE1 (0.42)	BACE1CTSDREN
SCHEMBL9848672	0.75	BACE1 (0.47)	BACE1CTSDREN
SCHEMBL11570483	0.74	CTSK (0.57)	BACE1
SCHEMBL20990367	0.74	BACE1 (0.41)	BACE1CTSD
SCHEMBL4638730	0.73	DPP4 (0.46)	—
SCHEMBL6558952	0.73	DPP4 (0.46)	—
SCHEMBL27601749	0.73	DPP4 (0.46)	—
SCHEMBL9848679	0.73	BACE1 (0.52)	BACE1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0438873-A1	Inhibitor of ribonucleotide reductase of herpes viruses	MERCK & CO. INC. (US)	1991-07-31	—	—	EP	disclosed