SCHEMBL9848774

SCHEMBL9848774

C=CCOCC(O)COC(OCC(O)COCC=C)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.44
ALDH1A1 P00352 4/20 0.38
TSHR P16473 1/20 0.38
CA1 P00915 4/20 0.38
CA2 P00918 4/20 0.38
CA7 P43166 4/20 0.38
CYP2D6 P10635 1/20 0.37
HTT P42858 1/20 0.37
CA4 P22748 3/20 0.36
CA9 Q16790 3/20 0.36
AKT1 P31749 1/20 0.34
CYP3A4 P08684 1/20 0.33
CTSK P43235 1/20 0.33
ADRB2 P07550 3/20 0.33
ADRB1 P08588 3/20 0.33
ADRB3 P13945 3/20 0.33
KDM4E B2RXH2 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL274928 0.82 CES1 (0.56) CES1ALDH1A1TSHRHTTAKT1
SCHEMBL27859924 0.80 CA1 (0.45) ALDH1A1TSHRCA1CA2CA7
SCHEMBL9860788 0.75 CES1 (0.67) CES1ALDH1A1TSHRHTTAKT1
SCHEMBL1970018 0.74 CA1 (0.41) ALDH1A1CA1CA2CA7CYP2D6
SCHEMBL20829174 0.74 CA1 (0.41) ALDH1A1TSHRCA1CA2CA7
SCHEMBL10398398 0.73 ALDH1A1 (0.47) CES1ALDH1A1TSHRHTTAKT1
SCHEMBL27907727 0.72 ABCB1 (0.56) ALDH1A1CYP2D6HTTKMT2A
SCHEMBL8007610 0.72 CTSK (0.39) CA1CA2CA7CYP2D6HTT
SCHEMBL20742533 0.72 CTSK (0.39) CA1CA2CA7CYP2D6HTT
SCHEMBL20742531 0.72 CTSK (0.39) CA1CA2CA7CYP2D6HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0456040-A1 Copolymerisable photoinitiators of the benzil ketal type CIBA-GEIGY AG (CH) 1991-11-13 EP disclosed