Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026142 | 1.00 | CCKBR (0.38) | CCKBRMEN1KMT2AGPR84CMA1 | |
| SCHEMBL9025971 | 1.00 | CCKBR (0.38) | CCKBRMEN1KMT2AGPR84CMA1 | |
| SCHEMBL9026074 | 0.82 | KMT2A (0.47) | MEN1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL9026218 | 0.82 | KMT2A (0.47) | MEN1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL9026403 | 0.80 | KDM4E (0.43) | CCKBRMEN1KMT2AGPR84CMA1 | |
| SCHEMBL9026865 | 0.80 | KDM4E (0.43) | CCKBRMEN1KMT2AGPR84CMA1 | |
| SCHEMBL9026296 | 0.72 | TACR3 (0.42) | — | |
| SCHEMBL10466586 | 0.70 | GPR84 (0.46) | CCKBRKMT2AGPR84CMA1KDM4E | |
| SCHEMBL10467137 | 0.67 | HDAC3 (0.48) | CCKBRMEN1KMT2AGPR84CMA1 | |
| SCHEMBL10467623 | 0.66 | GPR84 (0.43) | CCKBRMEN1KMT2AGPR84CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |