Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026863 | 0.73 | CLEC4M (0.34) | LMNAMAPTCLEC4MMMP2MMP3 | |
| SCHEMBL9026324 | 0.70 | JAK2 (0.36) | LMNAMAPTMMP2MMP3 | |
| SCHEMBL27257386 | 0.69 | JAK2 (0.39) | LMNAMAPTHTR2A | |
| SCHEMBL10642478 | 0.66 | HTR2C (0.55) | MTNR1AMTNR1BCLEC4MHTR2APKM | |
| SCHEMBL15836985 | 0.65 | TSHR (0.54) | MAPTCLEC4MPKM | |
| SCHEMBL9418838 | 0.64 | SMN1; SMN2 (0.52) | MAPTMTNR1AMTNR1BCLEC4MHTR2A | |
| SCHEMBL16686899 | 0.63 | NR4A2 (0.58) | LMNAMAPTMTNR1AMTNR1BHTR2A | |
| SCHEMBL10930498 | 0.62 | NR4A2 (0.51) | LMNAMAPTMTNR1AMTNR1BCLEC4M | |
| SCHEMBL9026483 | 0.62 | KDM4E (0.33) | LMNAMAPTMTNR1AMTNR1BHTR2A | |
| SCHEMBL28445014 | 0.61 | NR4A2 (0.52) | LMNAMAPTMTNR1AMTNR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |