Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27257386 | 0.86 | JAK2 (0.39) | JAK2JAK3GABRA1GABRB1GABRA3 | |
| SCHEMBL9026147 | 0.82 | KMT2A (0.40) | MEN1KMT2AL3MBTL1KDM4EMMP2 | |
| SCHEMBL9027482 | 0.79 | PCSK9 (0.38) | SMN1; SMN2MEN1HSP90AA1KMT2AKDM4E | |
| SCHEMBL9027221 | 0.78 | PDE10A (0.36) | SMN1; SMN2MEN1HSP90AA1KMT2AKDM4E | |
| SCHEMBL9026863 | 0.78 | CLEC4M (0.34) | GABRA1GABRB1GABRA3GABRB2MEN1 | |
| SCHEMBL27258448 | 0.78 | LMNA (0.39) | GABRA1GABRB1GABRA3GABRB2GABRP | |
| SCHEMBL9025363 | 0.77 | LTA4H (0.46) | MEN1HSP90AA1KMT2AKDM4EMMP2 | |
| SCHEMBL9026402 | 0.77 | GPR84 (0.45) | MEN1HSP90AA1KMT2AKDM4ETRPM8 | |
| SCHEMBL9026638 | 0.75 | KMT2A (0.39) | MEN1KMT2AL3MBTL1KDM4EMMP2 | |
| SCHEMBL9026084 | 0.75 | KCNA5 (0.38) | MEN1KMT2AIL1RNERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |