Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026483 | 0.90 | KDM4E (0.33) | ALDH1A1KDM4EGAAMMP2CDK2 | |
| SCHEMBL9025829 | 0.79 | MAPT (0.42) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL9026324 | 0.78 | JAK2 (0.36) | ALDH1A1KDM4EMMP2MMP3MEN1 | |
| SCHEMBL9026223 | 0.75 | PCSK9 (0.39) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL9027098 | 0.75 | SOS2 (0.43) | MAPT | |
| SCHEMBL9026796 | 0.74 | HTR2C (0.44) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL9026487 | 0.74 | AHR (0.39) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL9848986 | 0.73 | LMNA (0.32) | CLEC4MMMP2MMP3LMNAMAPT | |
| SCHEMBL9027577 | 0.73 | MAPT (0.41) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9026518 | 0.73 | GPR84 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |