Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28144480 | 0.80 | EEF2K (0.38) | ALDH1A1LMNAKDM4EGAAADORA2A | |
| SCHEMBL10858163 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2HTTKDM4E | |
| SCHEMBL11611108 | 0.76 | ALDH1A1 (0.38) | ALDH1A1LMNASMN1; SMN2HTTKDM4E | |
| SCHEMBL4759804 | 0.75 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2HTTKDM4E | |
| SCHEMBL9849014 | 0.68 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2HTTKDM4E | |
| SCHEMBL6887802 | 0.67 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2HTTKDM4E | |
| SCHEMBL11429505 | 0.65 | RGS4 (0.50) | ALDH1A1LMNASMN1; SMN2HTTADORA2A | |
| SCHEMBL4811164 | 0.65 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2HTTKMT2A | |
| SCHEMBL1545988 | 0.62 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL1546524 | 0.61 | SIRT1 (0.41) | ALDH1A1LMNASMN1; SMN2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407651-A2 | Use of 1,3-diisobutyl-8-methylxanthine as a bronchodilator and antiallergy agent | J. URIACH & CIA. S.A. (ES) | 1991-01-16 | — | — | EP | disclosed |