Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15826660 | 1.00 | CYP3A4 (0.50) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| SCHEMBL20749391 | 0.97 | LMNA (0.45) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| Bromide SCHEMBL15826377 | 0.94 | MEN1 (0.50) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| Water SCHEMBL5414875 | 0.94 | LMNA (0.43) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28345549 | 0.92 | CYP3A4 (0.48) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15821795 | 0.92 | CYP3A4 (0.48) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| SCHEMBL2143447 | 0.91 | LMNA (0.42) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15820823 | 0.89 | CYP3A4 (0.46) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| Water SCHEMBL2780523 | 0.88 | LMNA (0.40) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2444152 | 0.87 | CYP3A4 (0.62) | CYP3A4SLC5A7LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405967-A2 | Built liquid detergent compositions | Amway Corporation (US) | 1991-01-02 | — | — | EP | disclosed |