Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15821795 | 1.00 | CYP3A4 (0.48) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15820823 | 0.97 | CYP3A4 (0.46) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| Bromide SCHEMBL15822036 | 0.94 | MEN1 (0.48) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| Bromide SCHEMBL15820235 | 0.92 | DNM1 (0.48) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15826660 | 0.92 | CYP3A4 (0.50) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9849243 | 0.92 | CYP3A4 (0.50) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| SCHEMBL21405556 | 0.91 | SMN1; SMN2 (0.42) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| SCHEMBL20749391 | 0.88 | LMNA (0.45) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| SCHEMBL21405560 | 0.88 | MEN1 (0.45) | CYP3A4SLC5A7LMNAMEN1KMT2A | |
| Water SCHEMBL3306871 | 0.88 | SMN1; SMN2 (0.40) | CYP3A4SLC5A7LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655885-A | Sizing agent and preparation method and application thereof | 一汽解放汽车有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116236561-A | Collagen supermolecular body and preparation method and application thereof | 北京理工大学重庆创新中心 | 2023-06-09 | — | — | CN | claimed |
| CN-115670984-A | Shampoo containing volcanic mud and preparation method thereof | 五大连池风景区妍泥生物科技有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-112438927-A | Sea salt mite-removing acne-removing clean and fragrant body wash and production method thereof | 广州江莱化妆品有限公司 | 2021-03-05 | — | — | CN | claimed |
| CN-110652484-A | Shampoo formula for daily maintenance of psoriasis skin | 武汉赛锐希斯科技有限公司 | 2020-01-07 | — | — | CN | claimed |
| CN-118510394-A | Antimicrobial systems with indole alkaloids and phenolic acids and compositions containing them | 联合利华知识产权控股有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-118488786-A | Antimicrobial systems with beta-carboline alkaloids and indole alkaloids and compositions containing them | 联合利华知识产权控股有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-118414085-A | Antimicrobial systems with beta carboline alkaloids and phenolic acids and compositions containing them | 联合利华知识产权控股有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-111526860-B | Personal care compositions | 高露洁-棕榄公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117344554-A | Basalt fiber anti-discoloration water-based paint, preparation method and basalt fiber product | 中科瑞丽分离科技无锡有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-116847871-A | Skin care compositions and methods of use | 现代牧场股份有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116655885-A | Sizing agent and preparation method and application thereof | 一汽解放汽车有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116236561-A | Collagen supermolecular body and preparation method and application thereof | 北京理工大学重庆创新中心 | 2023-06-09 | — | — | CN | disclosed |
| CN-116173190-A | Collagen carrier, collagen nanoparticle, and preparation methods and applications thereof | 北京理工大学重庆创新中心 | 2023-05-30 | — | — | CN | disclosed |
| CN-115670984-A | Shampoo containing volcanic mud and preparation method thereof | 五大连池风景区妍泥生物科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-113559105-A | Treatment of resistant acne | 维奥姆治疗有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-106163526-B | Treatment of resistant acne | 维奥姆治疗有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-112438927-A | Sea salt mite-removing acne-removing clean and fragrant body wash and production method thereof | 广州江莱化妆品有限公司 | 2021-03-05 | — | — | CN | disclosed |
| CN-111526860-A | Personal care compositions | 高露洁-棕榄公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-110652484-A | Shampoo formula for daily maintenance of psoriasis skin | 武汉赛锐希斯科技有限公司 | 2020-01-07 | — | — | CN | disclosed |