Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | CASP1 | P29466 | 2/20 | 0.62 |
| ▸ | CASP7 | P55210 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CLK1 | P49759 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | SOD1 | P00441 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849531 | 0.77 | ALDH1A1 (0.67) | POLBALDH1A1PKMSMN1; SMN2KDM4E | |
| SCHEMBL9849419 | 0.75 | ALDH1A1 (0.61) | POLBALDH1A1PKMSMN1; SMN2KDM4E | |
| SCHEMBL9849298 | 0.74 | ALDH1A1 (0.72) | POLBALDH1A1PKMSMN1; SMN2KDM4E | |
| SCHEMBL9849540 | 0.73 | ALDH1A1 (0.58) | POLBALDH1A1PKMSMN1; SMN2KDM4E | |
| SCHEMBL9489057 | 0.71 | SMN1; SMN2 (0.78) | POLBALDH1A1PKMSMN1; SMN2KDM4E | |
| SCHEMBL9849546 | 0.70 | ALDH1A1 (0.58) | POLBALDH1A1PKMSMN1; SMN2KDM4E | |
| SCHEMBL9849551 | 0.70 | ALDH1A1 (0.60) | POLBALDH1A1PKMSMN1; SMN2KDM4E | |
| SCHEMBL1641286 | 0.66 | SMN1; SMN2 (0.69) | POLBALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL49130 | 0.65 | L3MBTL1 (0.66) | POLBALDH1A1SMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL11485517 | 0.64 | POLB (0.70) | POLBALDH1A1PKMSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |