Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CASP1 | P29466 | 2/20 | 0.58 |
| ▸ | CASP7 | P55210 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CLK1 | P49759 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849531 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL9849532 | 0.78 | KDM4E (0.54) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL9849422 | 0.77 | QPCT (0.57) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL9849419 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL9849398 | 0.76 | L3MBTL1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL9849543 | 0.75 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL9849546 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL9849551 | 0.73 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL9849396 | 0.73 | POLB (0.66) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL9849298 | 0.71 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |