Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849445 | 0.84 | PPARA (0.51) | PPARAPOLBSMN1; SMN2RAB9ANPC1 | |
| Ammonia Solution, Strong SCHEMBL9548251 | 0.83 | PPARA (0.50) | PPARAPOLBSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9548246 | 0.83 | PPARA (0.45) | PPARAPOLBSMN1; SMN2CYP1A2RAB9A | |
| SCHEMBL11661758 | 0.81 | PPARA (0.60) | PPARAPOLBSMN1; SMN2CYP1A2RAB9A | |
| SCHEMBL9849248 | 0.78 | PPARA (0.54) | PPARAPOLBSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL18031837 | 0.78 | POLB (0.50) | POLBSMN1; SMN2CYP1A2RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL9548242 | 0.77 | SLC15A1 (0.47) | POLBSMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL27348673 | 0.76 | PPARA (0.52) | PPARAPOLBSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9548278 | 0.76 | PPARA (0.52) | PPARAPOLBSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9548297 | 0.76 | PPARA (0.52) | PPARASMN1; SMN2RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5273989-A | 3,5-disubstituted 2-isoxazolines and isoxazoles, agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | claimed |
| EP-0451790-A1 | 3,5-disubstituted 2-isoxazolines and isoxazoles, process for their preparation, medicines containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-16 | — | — | EP | claimed |
| US-5273989-A | 3,5-disubstituted 2-isoxazolines and isoxazoles, agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| EP-0451790-A1 | 3,5-disubstituted 2-isoxazolines and isoxazoles, process for their preparation, medicines containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-16 | — | — | EP | disclosed |