Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.75 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849509 | 0.96 | SMYD3 (0.77) | SMYD3SIGMAR1POLBHTTEPHX2 | |
| SCHEMBL19701393 | 0.87 | SMYD3 (0.80) | SMYD3SIGMAR1POLBHTTEPHX2 | |
| SCHEMBL21489802 | 0.87 | SMYD3 (0.80) | SMYD3SIGMAR1POLBHTTEPHX2 | |
| SCHEMBL19710237 | 0.86 | SMYD3 (1.00) | SMYD3SIGMAR1POLBHTTEPHX2 | |
| SCHEMBL21490108 | 0.86 | SMYD3 (1.00) | SMYD3SIGMAR1POLBHTTEPHX2 | |
| SCHEMBL17896307 | 0.85 | EPHX2 (0.63) | SMYD3SIGMAR1POLBHTTEPHX2 | |
| SCHEMBL11952076 | 0.84 | SMYD3 (0.56) | SMYD3SIGMAR1POLBHTTEPHX2 | |
| SCHEMBL11949279 | 0.83 | SMYD3 (0.57) | SMYD3SIGMAR1POLBHTTEPHX2 | |
| SCHEMBL7187522 | 0.82 | SIGMAR1 (0.70) | SIGMAR1ACKR3ALDH1A1 | |
| SCHEMBL19254907 | 0.81 | NPC1 (0.65) | SMYD3SIGMAR1POLBEPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415185-A1 | 4-Alkoxy- and 4-(substituted)amino-3-arylpyrrolinones derivatives | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |