Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | QPCT | Q16769 | 8/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 2/20 | 0.46 |
| ▸ | FNTB | P49356 | 2/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849422 | 0.79 | QPCT (0.57) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3631942 | 0.78 | QPCT (0.52) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9849540 | 0.78 | ALDH1A1 (0.58) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3631599 | 0.77 | QPCT (0.50) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9849543 | 0.77 | ALDH1A1 (0.49) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3630133 | 0.77 | QPCT (0.54) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9849531 | 0.69 | ALDH1A1 (0.67) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9849298 | 0.67 | ALDH1A1 (0.72) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9849546 | 0.67 | ALDH1A1 (0.58) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8379438 | 0.67 | QPCT (0.50) | ALDH1A1QPCTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |