Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | QPCT | Q16769 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | SOD1 | P00441 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849422 | 0.88 | QPCT (0.57) | ALDH1A1KDM4ELMNAPOLBHPGD | |
| SCHEMBL9849628 | 0.84 | KDM4E (0.56) | ALDH1A1KDM4ELMNAPOLBHPGD | |
| SCHEMBL9849532 | 0.77 | KDM4E (0.54) | ALDH1A1KDM4ELMNAPOLBHPGD | |
| SCHEMBL3631542 | 0.77 | KDM4E (0.49) | ALDH1A1KDM4ELMNAPOLBHPGD | |
| SCHEMBL3633387 | 0.77 | GSK3A (0.53) | ALDH1A1KDM4ELMNAHSD17B10GAA | |
| SCHEMBL3632700 | 0.76 | GSK3A (0.48) | ALDH1A1KDM4EHPGDGAAQPCT | |
| SCHEMBL9849540 | 0.75 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAPOLBHPGD | |
| SCHEMBL3632000 | 0.74 | SMN1; SMN2 (0.54) | ALDH1A1KDM4EHPGDGAAQPCT | |
| SCHEMBL3631375 | 0.74 | CTSK (0.48) | ALDH1A1KDM4ELMNAHPGDGAA | |
| SCHEMBL3633391 | 0.74 | GSK3A (0.54) | ALDH1A1KDM4EHSD17B10GAAQPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |