Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340019 | 0.88 | LMNA (0.48) | LMNA | |
| SCHEMBL9341852 | 0.88 | LMNA (0.47) | LMNAALDH1A1TSHR | |
| SCHEMBL9850062 | 0.81 | LMNA (0.44) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9122701 | 0.81 | LMNA (0.55) | LMNAMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8815820 | 0.80 | LMNA (0.51) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8816740 | 0.73 | TSHR (0.56) | LMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL9340035 | 0.70 | TSHR (0.50) | LMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL9140399 | 0.70 | EPHX2 (0.67) | MEN1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8813660 | 0.70 | TSHR (0.52) | LMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL8813227 | 0.69 | ALDH1A1 (0.46) | LMNAMEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462933-A1 | Novel N-benzyl-N1-phenyl and -phenalkyl-thioureas | SANDOZ LTD. (CH) | 1991-12-27 | — | — | EP | disclosed |