Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.37 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | NAT1 | P18440 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3679517 | 0.78 | CYP2C9 (0.35) | KMT2AALDH1A1MEN1SIRT1CYP3A4 | |
| SCHEMBL28591333 | 0.77 | L3MBTL1 (0.42) | SIGMAR1HTTKMT2ATXNRD1TXNRD3 | |
| SCHEMBL9850089 | 0.73 | ATM (0.40) | KMT2AALDH1A1NPSR1MEN1CA9 | |
| SCHEMBL9326126 | 0.67 | SIGMAR1 (0.55) | SIGMAR1HTTKMT2AALDH1A1OPRM1 | |
| SCHEMBL8747300 | 0.66 | SIGMAR1 (0.46) | SIGMAR1HTTKMT2AALDH1A1OPRM1 | |
| SCHEMBL19291033 | 0.65 | SIGMAR1 (0.53) | SIGMAR1HTTKMT2AALDH1A1OPRM1 | |
| SCHEMBL28302026 | 0.65 | SIGMAR1 (0.49) | SIGMAR1HTTKMT2AALDH1A1OPRM1 | |
| SCHEMBL30211173 | 0.65 | SMN1; SMN2 (0.42) | KMT2ANPSR1MEN1OPRM1OPRD1 | |
| SCHEMBL2046175 | 0.64 | SIGMAR1 (0.51) | SIGMAR1HTTKMT2AALDH1A1HPGD | |
| SCHEMBL1132825 | 0.64 | SIGMAR1 (0.51) | SIGMAR1HTTKMT2AALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423482-A1 | 5H-furan-2-one derivatives | BAYER AG (DE) | 1991-04-24 | — | — | EP | disclosed |