Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3679517 | 0.74 | CYP2C9 (0.35) | CYP3A4MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL9850087 | 0.73 | SIGMAR1 (0.41) | CYP3A4ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL1533059 | 0.72 | HSD11B1 (0.36) | — | |
| SCHEMBL7033227 | 0.67 | LMNA (0.44) | ALDH1A1CYP19A1MEN1KMT2ALMNA | |
| SCHEMBL7212713 | 0.66 | ACHE (0.45) | ATMKDM4EACHEMAPTCYP3A4 | |
| SCHEMBL10985710 | 0.66 | CYP3A4 (0.42) | ATMKDM4EACHEMAPTCYP3A4 | |
| SCHEMBL9721261 | 0.66 | LMNA (0.41) | ATMKDM4EACHEMAPTCYP3A4 | |
| SCHEMBL8563574 | 0.65 | MAPT (0.44) | KDM4EACHEMAPTCYP3A4ALDH1A1 | |
| SCHEMBL28893222 | 0.64 | MAPT (0.54) | KDM4EACHEMAPTCYP3A4ALDH1A1 | |
| SCHEMBL9719037 | 0.64 | MAPT (0.54) | KDM4EACHEMAPTCYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423482-A1 | 5H-furan-2-one derivatives | BAYER AG (DE) | 1991-04-24 | — | — | EP | claimed |
| EP-0423482-A1 | 5H-furan-2-one derivatives | BAYER AG (DE) | 1991-04-24 | — | — | EP | disclosed |